PT-141 Oxytocin Nasal Stack

Product Overview

The PT-141 Oxytocin Nasal Stack, available exclusively through Direct Anti Peptide, represents a precision-formulated dual-peptide research solution designed to support scientific investigation into the intersection of melanocortin receptor activity and oxytocinergic neuroendocrine pathways. PT-141, also known by its chemical designation Bremelanotide, is a synthetic cyclic heptapeptide recognized for its affinity toward melanocortin receptors, particularly MC3R and MC4R, within the central nervous system. Oxytocin, often referred to in the scientific literature as the “love hormone” or “bonding neuropeptide,” is a naturally occurring nonapeptide synthesized in the hypothalamus and released via the posterior pituitary. Together, these two compounds offer researchers a rare combinatorial tool for studying overlapping pathways in arousal neuroscience, prosocial behavior, stress modulation, and mood regulation.

Peptide Structure & Amino Acid Sequence

PT-141 (Bremelanotide) is a cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH), with the sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. Its cyclic architecture confers enhanced receptor selectivity and metabolic stability compared to its linear precursor, Melanotan II. Oxytocin is a nonapeptide with the sequence: Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH₂, characterized by a disulfide bridge between the two cysteine residues at positions 1 and 6, which is critical to its biological receptor-binding conformation.

Chemical & Physical Characteristics

• PT-141 (Bremelanotide): Molecular Formula — C₅₀H₆₈N₁₄O₁₀; Molecular Weight — 1025.17 g/mol; CAS Number — 189691-06-3
• Oxytocin: Molecular Formula — C₄₃H₆₆N₁₂O₁₂S₂; Molecular Weight — 1007.19 g/mol; CAS Number — 50-56-6
• Both peptides appear as white to off-white lyophilized powders prior to formulation
• The nasal stack solution is prepared in a sterile aqueous carrier optimized for intranasal research delivery systems
• Solubility: Both peptides exhibit favorable aqueous solubility at physiological pH ranges relevant to nasal mucosal research models

Purity & Analytical Verification (HPLC & MS)

Every batch of the PT-141 Oxytocin Nasal Stack sold at Direct Anti Peptide is manufactured to a minimum purity of ≥98%, verified through high-performance liquid chromatography (HPLC) and confirmed by mass spectrometry (MS). These dual analytical methods ensure peptide identity, sequence integrity, and the absence of truncated sequences, oxidative byproducts, or residual synthesis impurities. Certificates of Analysis (CoA) are available upon request and reflect lot-specific testing data.

Quality Control & Lyophilization Integrity

Prior to nasal stack formulation, both PT-141 and Oxytocin peptide components undergo lyophilization under controlled freeze-drying conditions to preserve structural integrity and long-term stability. The lyophilization process removes residual moisture to levels below 5%, minimizing degradation risks during storage and transit. Each production lot undergoes multi-point quality control review encompassing endotoxin screening, sterility assessment, and concentration verification before release for research distribution.

Safety, Handling & Laboratory Precautions

This product is intended exclusively for use by qualified researchers and trained laboratory professionals operating within appropriately equipped facilities. Standard laboratory personal protective equipment (PPE) — including gloves, eye protection, and lab coats — should be worn at all times when handling this research material. Researchers should consult applicable institutional biosafety guidelines and local regulatory frameworks before initiating any study involving this compound. This product is not approved for human or animal administration under any circumstances.

Reconstitution, Packaging & Storage

The PT-141 Oxytocin Nasal Stack is supplied in a pre-formulated nasal delivery format, ready for application within approved in vitro or ex vivo research protocols. For long-term preservation, store the product at -20°C in a sealed, light-protected container. Once opened or reconstituted for research use, the solution should be stored at 2–8°C and used within the timeframe specified on the product CoA. Avoid repeated freeze-thaw cycles, which may compromise peptide stability and analytical accuracy.

Intended Research Use & Market Positioning

The PT-141 Oxytocin Nasal Stack is positioned as a premium combinatorial research reagent for academic institutions, neuropharmacology laboratories, and independent researchers studying melanocortin receptor signaling, hypothalamic neuropeptide function, prosocial behavior modeling, and neuroendocrine co-modulation. The synergistic pairing of Bremelanotide and Oxytocin within a single nasal delivery format makes this stack a uniquely efficient tool for investigating overlapping CNS pathways with a single, standardized research preparation.

Ordering, Availability & Fulfillment

Researchers looking to buy the PT-141 Oxytocin Nasal Stack online can order directly through Direct Anti Peptide with confidence. We offer competitive best-price positioning, rapid order processing, and secure, discreet fulfillment to research institutions worldwide. Our customer support team is available to assist with bulk ordering inquiries, CoA requests, and technical product questions. Order now to take advantage of our streamlined checkout and fast dispatch timelines.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. The PT-141 Oxytocin Nasal Stack is sold exclusively as a laboratory research reagent. Direct Anti Peptide makes no claims regarding the therapeutic, pharmacological, or physiological effects of this product in humans or animals. All purchasers are solely responsible for ensuring compliance with applicable local, national, and international laws and regulations governing the acquisition, possession, and use of research peptides. This product has not been evaluated or approved by the FDA, EMA, or any equivalent regulatory authority for use in humans or animals.