AICAR Peptide Vial

Direct Anti Peptide offers a high-purity AICAR Peptide Vial, manufactured to ≥98% purity and supplied in lyophilized form for advanced laboratory research applications. AICAR (5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside) is a well-characterized nucleotide precursor analogue recognized in scientific literature for its role in activating AMP-activated protein kinase (AMPK). For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

AICAR, also known as AICA ribonucleotide or acadesine, is a cell-permeable nucleoside analogue that functions as an endogenous AMPK activator within cellular systems. It has been widely studied in the context of metabolic regulation, energy homeostasis, and cellular signalling pathways. Researchers across biochemistry, pharmacology, and metabolic disease fields utilize AICAR as a reference compound to investigate AMPK-dependent mechanisms. Available exclusively for laboratory research purposes, this vial-format product from Direct Anti Peptide is optimized for precision, stability, and reproducibility in controlled research settings.

Peptide Structure & Amino Acid Sequence

AICAR is not a traditional peptide in the amino acid chain sense; rather, it is a mononucleotide intermediate in the purine biosynthesis pathway. Its chemical structure is that of a ribonucleoside monophosphate analogue: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside. Once taken up by cells, AICAR is phosphorylated to ZMP (AICAR monophosphate), which mimics AMP and directly activates AMPK. This mechanism makes it a uniquely valuable tool compound for researchers studying energy-sensing pathways and downstream metabolic targets.

Chemical & Physical Characteristics

• Chemical Name: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside
• Synonyms: Acadesine, AICA Ribonucleotide, ZMP precursor
• Molecular Formula: C₉H₁₄N₄O₅
• Molecular Weight: 258.23 g/mol
• CAS Number: 2627-69-2
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in aqueous buffer systems under standard laboratory conditions
• Form: Lyophilized solid in sterile glass vial

Purity & Analytical Verification (HPLC & MS)

Every batch of AICAR Peptide Vial supplied by Direct Anti Peptide is analytically verified to confirm a minimum purity of ≥98%. High-Performance Liquid Chromatography (HPLC) is employed as the primary method of purity assessment, with mass spectrometry (MS) used for molecular identity confirmation. These dual analytical methods ensure that each vial contains correctly identified, high-integrity compound material, free from significant impurities or degradation products. Certificates of Analysis (CoA) reflecting these results are available upon request for qualified research institutions.

Quality Control & Lyophilization Integrity

AICAR is supplied in lyophilized (freeze-dried) form to maximize long-term stability and minimize degradation during storage and transit. The lyophilization process removes residual moisture under vacuum conditions, preserving molecular integrity and ensuring batch-to-batch consistency. Each sterile glass vial is sealed under inert atmospheric conditions to prevent oxidative or hydrolytic degradation. Direct Anti Peptide applies rigorous quality control protocols at every stage of production and packaging to ensure that researchers receive a reliable, reproducible compound for their experimental workflows.

Safety, Handling & Laboratory Precautions

AICAR Peptide Vial is intended exclusively for use by trained laboratory professionals in properly equipped research facilities. Standard laboratory safety protocols must be observed at all times. Researchers should wear appropriate personal protective equipment (PPE) including gloves, lab coat, and eye protection when handling this compound. Avoid inhalation of lyophilized powder. This product is not approved for use in humans or animals and must not be used in any clinical, therapeutic, or consumptive context.

Reconstitution, Packaging & Storage

AICAR is packaged in a sealed, sterile glass vial suitable for laboratory reconstitution using appropriate aqueous solvents as determined by the researcher’s experimental protocol. Upon receipt, the lyophilized vial should be stored at -20°C in a dry, dark environment away from moisture and direct light. Reconstituted solutions should be aliquoted and stored according to established laboratory guidelines to prevent repeated freeze-thaw cycles that may compromise compound integrity. Refer to applicable institutional SOPs for reconstitution guidance.

Intended Research Use & Market Positioning

AICAR is one of the most extensively referenced AMPK-activating compounds in metabolic research literature. It is widely used in studies examining glucose uptake, fatty acid oxidation, mitochondrial biogenesis, and cellular energy sensing. Researchers investigating type 2 diabetes models, obesity-related metabolic dysfunction, and exercise mimetics frequently incorporate AICAR into their experimental designs. Direct Anti Peptide positions this product as a premium-grade, research-only reagent for academic, pharmaceutical, and biotechnology laboratory use.

Ordering, Availability & Fulfillment

Direct Anti Peptide makes it straightforward to buy AICAR Peptide Vial online at a competitive best price. Our streamlined ordering process, secure checkout, and reliable fulfillment infrastructure ensure that qualified researchers can order now with confidence. We maintain consistent stock levels to support ongoing research programs and offer prompt dispatch to laboratory destinations worldwide. For bulk or institutional orders, contact our team directly for pricing and availability.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. AICAR Peptide Vial is sold exclusively as a laboratory research reagent. Direct Anti Peptide makes no claims regarding therapeutic efficacy, safety for human administration, or suitability for any use outside of controlled scientific research. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international regulations governing the purchase, possession, and use of research compounds. This product must not be misused or redistributed for non-research purposes.