PT-141 Kisspeptin Peptide Stack

PT-141 Kisspeptin Peptide Stack from Direct Anti Peptide is a dual-compound research peptide stack supplied at ≥98% purity, independently verified by HPLC and mass spectrometry. This stack combines two well-characterized peptide compounds — PT-141 (Bremelanotide) and Kisspeptin — for advanced laboratory and preclinical research applications. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

The PT-141 Kisspeptin Peptide Stack represents a scientifically compelling dual-peptide research formulation available for sale at Direct Anti Peptide. PT-141, also referred to by its pharmacological name Bremelanotide, is a synthetic melanocortin receptor agonist derived from the endogenous peptide hormone alpha-MSH. Kisspeptin is a naturally occurring neuropeptide encoded by the KISS1 gene and is recognized in the scientific literature for its pivotal regulatory role in the hypothalamic-pituitary-gonadal (HPG) axis. Together, these two compounds form a research stack of significant interest to investigators studying neuroendocrine signaling, reproductive biology, and related physiological pathways.

Peptide Structure & Amino Acid Sequence

PT-141 (Bremelanotide) is a cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH), functioning as a non-selective agonist at melanocortin receptors MC1R, MC3R, MC4R, and MC5R. Its cyclic structure confers enhanced metabolic stability compared to linear analogs. Kisspeptin, alternatively known as metastin, is a 54-amino acid peptide in its full-length form, though shorter bioactive fragments (Kisspeptin-10, -13, -14, and -54) are widely studied. The biologically active C-terminal decapeptide sequence is responsible for GPR54 receptor binding, making it a key subject in HPG axis research. Both peptides in this stack are synthesized to research-grade specifications.

Chemical & Physical Characteristics

• PT-141 (Bremelanotide): Cyclic heptapeptide; CAS No. 189691-06-3; Molecular Formula C₅₀H₆₈N₁₄O₁₀; Molecular Weight approx. 1025.17 g/mol
• Kisspeptin: Neuropeptide; encoded by KISS1 gene; GPR54 receptor agonist; Molecular Weight varies by fragment (Kisspeptin-10 approx. 1302.5 g/mol)
• Both compounds appear as white to off-white lyophilized powder
• High aqueous solubility upon proper reconstitution under laboratory conditions
• Stable under recommended storage conditions prior to reconstitution

Purity & Analytical Verification (HPLC & MS)

Every batch of the PT-141 Kisspeptin Peptide Stack supplied by Direct Anti Peptide undergoes rigorous third-party analytical testing. Purity is confirmed at ≥98% via reverse-phase high-performance liquid chromatography (RP-HPLC). Molecular identity and structural integrity are further validated through mass spectrometry (MS) analysis. Certificates of Analysis (CoA) are available upon request and reflect lot-specific analytical data, ensuring researchers receive a product that meets the highest standards for preclinical investigation.

Quality Control & Lyophilization Integrity

Both peptide compounds within this stack are lyophilized using pharmaceutical-grade freeze-drying processes to preserve structural integrity, potency, and long-term stability. Lyophilization removes residual moisture to levels below 5%, minimizing degradation risk during transit and storage. Each vial is sealed under inert atmosphere conditions to prevent oxidative degradation. Batch-to-batch consistency is maintained through standardized synthesis and QC protocols, providing researchers with a reliable and reproducible research material.

Safety, Handling & Laboratory Precautions

This product is strictly intended for use by trained laboratory professionals in controlled research environments. Researchers should consult relevant Safety Data Sheets (SDS) prior to handling. Standard laboratory personal protective equipment (PPE) — including gloves, eye protection, and appropriate lab attire — should be worn at all times. Avoid inhalation of lyophilized powder. Handle under appropriate biosafety conditions consistent with institutional guidelines. This compound is not approved for any human, veterinary, clinical, or diagnostic application.

Reconstitution, Packaging & Storage

Upon receipt, store lyophilized peptide vials at −20°C in a dry, dark environment. Avoid repeated freeze-thaw cycles to preserve peptide integrity. Reconstitution should be performed using sterile, appropriate laboratory-grade solvents as determined by the principal investigator and institutional protocols — strictly for in vitro or approved preclinical use only. Once reconstituted, solutions should be aliquoted and stored at −80°C where extended stability is required. Packaging is designed to maintain product integrity during international transit and complies with applicable shipping standards for research biochemicals.

Intended Research Use & Market Positioning

The PT-141 Kisspeptin Peptide Stack is positioned for researchers investigating neuroendocrine regulation, reproductive endocrinology, melanocortin receptor pharmacology, and HPG axis signaling. This stack is of particular interest in studies examining the interplay between central melanocortin pathways and gonadotropin-releasing hormone (GnRH) secretion. Direct Anti Peptide offers this research stack for sale to qualified laboratory professionals and academic institutions seeking a competitively priced, high-purity dual-peptide research tool.

Ordering, Availability & Fulfillment

Researchers can order the PT-141 Kisspeptin Peptide Stack online directly through Direct Anti Peptide. We offer competitive best-price guarantees on all research peptides, with fast dispatch and reliable international fulfillment. All orders are processed with full compliance documentation. Contact our team for bulk order inquiries, institutional pricing, or CoA requests. Buy online today and benefit from our streamlined ordering process designed specifically for research professionals.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. The PT-141 Kisspeptin Peptide Stack is sold exclusively as a laboratory research reagent. Direct Anti Peptide makes no claims regarding therapeutic efficacy, safety for administration, or suitability for any use outside of controlled, approved preclinical research settings. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international laws and regulations governing the acquisition, possession, and use of research peptides. This product has not been evaluated or approved by any regulatory authority for human or animal use.