IGF-1 LR3 Nasal Spray

Direct Anti Peptide offers IGF-1 LR3 Nasal Spray at ≥98% purity, rigorously verified by HPLC and mass spectrometry, formulated exclusively for in vitro and laboratory research applications. This synthetic long-chain analogue of insulin-like growth factor-1 is supplied in a precision nasal spray format designed to support controlled scientific investigation. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

IGF-1 LR3 Nasal Spray is a high-purity research-grade peptide formulation available exclusively through Direct Anti Peptide for qualified laboratory and scientific research use. IGF-1 LR3 — formally known as Insulin-Like Growth Factor-1 Long Arg3 — is a synthetic analogue of endogenous IGF-1, engineered with a 13-amino acid extension at the N-terminus and an arginine substitution at position 3. These structural modifications significantly reduce IGF-binding protein affinity, resulting in a markedly extended half-life compared to native IGF-1. The nasal spray delivery format is selected by researchers for its practical laboratory administration characteristics, making it a sought-after format in peptide research procurement.

Peptide Structure & Amino Acid Sequence

IGF-1 LR3 is a 83-amino acid polypeptide analogue derived from the native 70-amino acid IGF-1 sequence. The LR3 modification incorporates a 13-residue N-terminal extension and a glutamic acid-to-arginine substitution at position 3. These alterations are specifically engineered to diminish binding affinity to IGF-binding proteins (IGFBPs), thereby prolonging systemic bioavailability in experimental models. The molecular formula is C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉, with a molecular weight of approximately 9,117 Da. Researchers studying anabolic signalling cascades, receptor binding kinetics, and cell proliferation pathways frequently select this analogue for its well-characterised structural profile.

Chemical & Physical Characteristics

IGF-1 LR3 presents as a white to off-white lyophilised powder prior to formulation. Key chemical and physical attributes include:

• Molecular Weight: ~9,117 Da
• Amino Acid Count: 83 residues
• Solubility: Soluble in aqueous buffers at appropriate pH
• Storage Form: Lyophilised powder reconstituted into nasal spray solution
• CAS-Related Class: Recombinant/synthetic IGF-1 analogue
• Purity: ≥98% as confirmed by analytical HPLC

Purity & Analytical Verification (HPLC & MS)

Every batch of IGF-1 LR3 Nasal Spray supplied by Direct Anti Peptide undergoes stringent analytical testing prior to release. Reverse-phase high-performance liquid chromatography (RP-HPLC) is employed to confirm peptide purity at ≥98%, while mass spectrometry (MS) validates molecular identity and confirms sequence integrity. Certificates of Analysis (CoA) are available upon request, providing full transparency over lot-specific purity data, retention times, and mass confirmation results. Researchers can order with confidence knowing each unit meets exacting quality benchmarks.

Quality Control & Lyophilisation Integrity

Prior to formulation into nasal spray format, the active peptide substrate is lyophilised under controlled freeze-drying conditions to preserve structural integrity and biological activity for research purposes. Lyophilisation removes residual moisture to levels that safeguard long-term peptide stability. Each production lot is subject to multi-point quality control checkpoints, including sterility screening, endotoxin testing, and physical appearance assessment, ensuring consistent and reproducible research-grade material across all units dispatched by Direct Anti Peptide.

Safety, Handling & Laboratory Precautions

IGF-1 LR3 Nasal Spray is strictly a laboratory research reagent. All handling must be performed by trained scientific professionals in appropriately equipped research facilities. Standard laboratory personal protective equipment (PPE) — including nitrile gloves, safety eyewear, and lab coats — should be worn at all times during handling. This material is not approved for administration to humans or animals under any circumstances. Researchers must adhere to all applicable institutional biosafety protocols and local regulatory requirements when working with this compound.

Reconstitution, Packaging & Storage

IGF-1 LR3 Nasal Spray is supplied in a ready-to-use nasal spray format, pre-formulated for laboratory research convenience. Packaging is designed to maintain peptide stability throughout transit and storage. Recommended storage conditions are 2–8°C under refrigeration, away from direct light and moisture. Avoid repeated freeze-thaw cycles. For extended storage prior to use, consult the CoA for lot-specific guidance. All packaging is labelled clearly for research use identification and regulatory traceability.

Intended Research Use & Market Positioning

IGF-1 LR3 is actively investigated in peer-reviewed research contexts exploring anabolic signalling, tissue repair mechanisms, cell proliferation, metabolic regulation, and growth factor receptor interactions. Its extended half-life relative to native IGF-1 makes it particularly valuable in longitudinal in vitro studies. Direct Anti Peptide positions this product as a premium, competitively priced research reagent for academic institutions, pharmaceutical research organisations, and independent laboratories requiring reliable, high-purity IGF-1 LR3 at the best price available online.

Ordering, Availability & Fulfillment

IGF-1 LR3 Nasal Spray is available to buy online now through Direct Anti Peptide with straightforward ordering, secure checkout, and prompt dispatch. Our fulfillment process prioritises cold-chain integrity during shipping to preserve peptide quality upon arrival. Bulk research procurement inquiries are welcomed. Order now to benefit from competitive pricing, fast turnaround, and dedicated customer support from a trusted research peptide supplier.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. IGF-1 LR3 Nasal Spray is sold exclusively as a laboratory research reagent by Direct Anti Peptide. This product has not been evaluated or approved by any regulatory authority for therapeutic, prophylactic, or diagnostic use. Purchasers are solely responsible for ensuring compliance with all applicable national and international laws, institutional guidelines, and regulatory frameworks governing the procurement and use of research peptides. Direct Anti Peptide accepts no liability for misuse, improper handling, or non-compliant application of this product.