PT-141 Oxytocin Peptide Stack

Product Overview

The PT-141 Oxytocin Peptide Stack, available to order online at Direct Anti Peptide, combines two distinct and well-characterised research peptides into a single, convenient stack. PT-141 (Bremelanotide) is a synthetic melanocortin receptor agonist with documented activity at MC3R and MC4R receptor subtypes, making it a subject of significant interest in studies of central nervous system-mediated arousal pathways. Oxytocin, a nine-amino-acid neuropeptide endogenous to the hypothalamus, is widely investigated for its roles in prosocial behaviour, emotional regulation, and neuroendocrine stress response. Together, this research peptide stack offers qualified investigators a dual-peptide tool for exploring the intersection of these two distinct but potentially complementary biological systems.

Peptide Structure & Amino Acid Sequence

PT-141 is a cyclic heptapeptide derived from alpha-melanocyte-stimulating hormone (α-MSH), with the sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. Its cyclic structure confers enhanced metabolic stability relative to its linear precursors. Oxytocin is a nonapeptide with the sequence Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH₂, featuring a disulfide bridge between Cys¹ and Cys⁶ that is integral to its three-dimensional conformation and receptor-binding activity. Both peptides are synthesised via solid-phase peptide synthesis (SPPS) using Fmoc chemistry, ensuring sequence fidelity and consistent batch-to-batch reproducibility.

Chemical & Physical Characteristics

• PT-141 (Bremelanotide): Molecular Formula C₅₀H₆₈N₁₄O₁₀, Molecular Weight ~1025.2 Da, CAS 189691-06-3
• Oxytocin: Molecular Formula C₄₃H₆₆N₁₂O₁₂S₂, Molecular Weight ~1007.2 Da, CAS 50-56-6
• Both peptides are supplied as white to off-white lyophilised powders
• Both are freely soluble in aqueous buffers and standard laboratory solvents
• Isoelectric points and solubility profiles are consistent with published pharmacopoeial references

Purity & Analytical Verification (HPLC & MS)

Every batch of the PT-141 Oxytocin Peptide Stack supplied by Direct Anti Peptide undergoes rigorous third-party analytical testing prior to release. High-performance liquid chromatography (HPLC) analysis confirms a purity level of ≥98% for both PT-141 and Oxytocin components. Mass spectrometry (MS) verification confirms correct molecular weight and the absence of truncated sequences, deletion products, or residual protecting groups. Certificates of Analysis (CoA) reflecting these results are available upon request, providing researchers with the documentary evidence required for GLP-compliant laboratory records.

Quality Control & Lyophilisation Integrity

Both peptides within this stack are produced under strict quality management conditions and subjected to multi-stage quality control protocols. Lyophilisation is performed under controlled vacuum conditions to remove residual moisture, preserving peptide integrity and extending shelf stability. Residual moisture content is maintained below accepted thresholds to prevent hydrolytic degradation. Each vial is visually inspected and sealed under inert atmosphere to prevent oxidative damage, particularly relevant for the disulfide-containing Oxytocin component.

Safety, Handling & Laboratory Precautions

This product is intended exclusively for use by trained research professionals operating within appropriately equipped laboratory environments. Standard laboratory personal protective equipment (PPE), including gloves, eye protection, and a laboratory coat, should be worn at all times when handling lyophilised peptide material. Researchers should consult the relevant Safety Data Sheet (SDS) prior to use. This stack must not be used in any human or animal subject research without full institutional ethical approval and applicable regulatory authorisation. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Reconstitution, Packaging & Storage

The PT-141 Oxytocin Peptide Stack is packaged as two separate lyophilised vials to maintain individual peptide stability and allow independent handling during experimental workflows. Reconstitution should be performed using appropriate laboratory-grade solvents as determined by the researcher’s specific assay requirements. Upon reconstitution, aliquoting into single-use volumes is recommended to minimise freeze-thaw cycling. Lyophilised vials should be stored at -20°C in a dry, dark environment. Reconstituted solutions should be stored at 4°C and used within a timeframe consistent with established stability data for each peptide.

Intended Research Use & Market Positioning

This peptide stack is positioned as a premium dual-peptide research tool for investigators studying the neuroendocrine basis of arousal, social cognition, and emotional regulation. Research applications include in-vitro receptor binding assays, ex-vivo tissue studies, and preclinical model investigations examining the interplay between melanocortin signalling and oxytocinergic pathways. The stack is particularly relevant to research programmes exploring conditions such as hypoactive sexual desire disorder (HSDD) and emotional dysregulation at a mechanistic level. Direct Anti Peptide offers this stack at a competitive best price, making it an accessible option for laboratories seeking high-purity, analytically verified peptide reagents.

Ordering, Availability & Fulfillment

The PT-141 Oxytocin Peptide Stack is available to buy online now at Direct Anti Peptide with straightforward ordering, secure checkout, and prompt dispatch. Orders are fulfilled with careful cold-chain-compatible packaging to preserve lyophilised integrity during transit. Our team is available to assist with documentation requests, including CoA provision and bulk order enquiries. Order now to take advantage of our best-price guarantee and reliable, research-grade supply.

Legal & Regulatory Disclaimer

This product is sold strictly as a research reagent for qualified scientific and laboratory use only. It is not approved for, nor intended for, any human or veterinary application, self-administration, clinical use, diagnostic procedure, or consumptive purpose. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international laws and regulations governing the acquisition, possession, and use of research peptides. Direct Anti Peptide accepts no liability for misuse or use outside the scope of legitimate scientific research. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.