PT-141 Peptide Vial (Bremelanotide)

Direct Anti Peptide supplies PT-141 (Bremelanotide) as a high-purity, lyophilized research peptide intended exclusively for qualified scientific investigators and laboratory professionals. Produced to ≥98% purity and verified by HPLC and mass spectrometry, this vial is an ideal reference compound for studies exploring melanocortin receptor pharmacology. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

PT-141, scientifically designated Bremelanotide, is a cyclic heptapeptide analogue derived from the Melanotan II scaffold. It functions as a potent melanocortin receptor agonist — specifically at MC1R, MC3R, MC4R, and MC5R subtypes — and has attracted substantial academic interest due to its central nervous system activity profile. Unlike vascular-targeted compounds, PT-141 exerts its pharmacodynamic effects primarily through CNS melanocortin pathways, making it a structurally and mechanistically distinct tool compound for in vitro and in vivo receptor research. Direct Anti Peptide offers this compound for sale to licensed research institutions, pharmaceutical development teams, and academic laboratories seeking a reliable, high-purity reference standard.

Peptide Structure & Amino Acid Sequence

PT-141 (Bremelanotide) is a cyclic lactam peptide with the amino acid sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. Its molecular formula is C₅₀H₆₈N₁₄O₁₀, with a molecular weight of approximately 1025.2 g/mol and CAS number 189691-06-3. The cyclic structure confers enhanced metabolic stability compared to linear analogues, which is a key reason this peptide is widely selected as a research tool in receptor binding assays and structural pharmacology studies. The D-Phe substitution at position four further increases receptor selectivity and resistance to enzymatic degradation, properties of significant interest to peptide chemists and pharmacologists.

Chemical & Physical Characteristics

• Synonyms: Bremelanotide, PT-141
• CAS Number: 189691-06-3
• Molecular Formula: C₅₀H₆₈N₁₄O₁₀
• Molecular Weight: ~1025.2 g/mol
• Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in aqueous buffers; research-grade solvents recommended
• Storage Temperature: −20°C (long-term); +4°C (short-term, desiccated)

Purity & Analytical Verification (HPLC & MS)

Every batch of PT-141 supplied by Direct Anti Peptide undergoes rigorous analytical testing prior to release. Purity is confirmed at ≥98% using reverse-phase high-performance liquid chromatography (RP-HPLC). Molecular identity is independently validated by mass spectrometry (MS), ensuring the correct molecular weight and structural integrity of each vial. Certificate of Analysis (CoA) documentation is available upon request, providing full transparency of batch-specific analytical data for regulatory and publication purposes.

Quality Control & Lyophilization Integrity

PT-141 from Direct Anti Peptide is produced under stringent quality control conditions. The lyophilization process is performed using validated freeze-drying protocols that preserve peptide conformation, prevent aggregation, and maximize long-term stability. Each vial is sealed under inert atmosphere conditions to prevent oxidative degradation. Batch traceability is maintained throughout the manufacturing chain, from synthesis to dispatch, ensuring full accountability for research-grade procurement requirements.

Safety, Handling & Laboratory Precautions

PT-141 is a potent biological research compound and must be handled exclusively by trained laboratory personnel in accordance with applicable institutional biosafety guidelines. Standard laboratory personal protective equipment (PPE) — including nitrile gloves, safety glasses, and a laboratory coat — should be worn at all times during handling. Avoid inhalation of lyophilized powder. This compound is not approved for any human or animal administration. Disposal must comply with local regulations governing research chemical waste. Direct Anti Peptide assumes no liability for improper use outside of controlled research environments.

Reconstitution, Packaging & Storage

PT-141 is supplied as a lyophilized solid in a sealed, sterile-grade vial suitable for laboratory reconstitution using appropriate research-grade solvents (e.g., bacteriostatic water or sterile aqueous buffers — for in vitro assay use only). Store lyophilized product at −20°C in a desiccated environment, protected from light and moisture. Once reconstituted for assay purposes, aliquot and store at −80°C to minimise freeze-thaw degradation. Packaging is designed for research laboratory use and complies with standard cold-chain shipping requirements.

Intended Research Use & Market Positioning

PT-141 (Bremelanotide) is a widely cited tool compound in published pharmacological literature examining melanocortin receptor biology, CNS signalling pathways, and receptor subtype selectivity. It is actively ordered by academic research groups, contract research organisations (CROs), and pharmaceutical preclinical teams. Direct Anti Peptide positions this compound as a premium-grade, competitively priced research peptide for sale, offering consistent batch-to-batch quality that supports reproducible experimental outcomes. Researchers seeking to buy PT-141 online will find our platform offers transparent CoA access, fast dispatch, and reliable international fulfillment.

Ordering, Availability & Fulfillment

PT-141 (Bremelanotide) is available to order now through the Direct Anti Peptide online store. We offer competitive best-price positioning for bulk and single-vial orders, with streamlined checkout, secure payment processing, and discreet laboratory-grade packaging. Orders are processed promptly, with tracked international shipping available to qualified research destinations. For institutional purchasing, volume pricing, or CoA requests, contact our research accounts team directly.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. PT-141 (Bremelanotide) is sold exclusively as a laboratory research compound by Direct Anti Peptide. It is the sole responsibility of the purchasing institution to ensure compliance with all applicable local, national, and international laws governing the procurement, storage, and use of research peptides. This product has not been evaluated by any regulatory authority for safety or efficacy in humans or animals. Direct Anti Peptide makes no therapeutic claims and accepts no liability for misuse of this compound beyond its stated research purpose.