IGF-1 LR3 Peptide Vial

Direct Anti Peptide supplies IGF-1 LR3 Peptide Vial at ≥98% purity, produced as a lyophilised powder in a sterile glass vial and verified by HPLC and mass spectrometry. This synthetic analogue of Insulin-like Growth Factor-1 is available exclusively for qualified laboratory and scientific research applications. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

IGF-1 LR3 — formally designated Long R3 Insulin-like Growth Factor-1 — is a synthetic, structurally modified analogue of endogenous IGF-1. The modification replaces glutamic acid at position 3 with arginine and appends a 13-amino-acid N-terminal extension, yielding an 83-amino-acid chain with significantly reduced binding affinity for IGF-binding proteins. This pharmacokinetic profile makes IGF-1 LR3 a widely studied research tool for investigating cellular proliferation, protein synthesis pathways, and metabolic signalling in controlled in vitro and in vivo laboratory models. Direct Anti Peptide offers this compound for sale to verified research institutions and licensed professionals seeking a reliable, high-purity supply.

Peptide Structure & Amino Acid Sequence

IGF-1 LR3 is an 83-amino-acid polypeptide derived from the native 70-amino-acid IGF-1 sequence. Key structural features include:

• N-terminal extension: A 13-residue leader sequence that reduces IGF-binding protein interactions and extends biological half-life in experimental systems.
• Substitution at position 3: Arginine replaces glutamic acid, further attenuating binding-protein affinity.
• Three intramolecular disulfide bonds: Retained from native IGF-1, preserving tertiary folding critical for receptor-binding studies.
• Molecular weight: Approximately 9,117 Da.

This architecture makes IGF-1 LR3 a preferred research reagent when investigators require prolonged receptor engagement relative to the native isoform.

Chemical & Physical Characteristics

• Sequence length: 83 amino acids
• Molecular formula: C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉
• Molecular weight: ~9,117 Da
• Appearance: White to off-white lyophilised powder
• Solubility: Soluble in aqueous buffers under standard laboratory conditions
• Storage temperature: −20 °C (long-term); 2–8 °C (short-term, up to 4 weeks)

Purity & Analytical Verification (HPLC & MS)

Every batch of IGF-1 LR3 supplied by Direct Anti Peptide undergoes rigorous analytical testing prior to release. Purity is confirmed at ≥98% by reverse-phase high-performance liquid chromatography (RP-HPLC), and molecular identity is validated by electrospray ionisation mass spectrometry (ESI-MS). Certificates of Analysis (CoA) are available upon request, providing full traceability of chromatographic and spectral data. Researchers can order with confidence knowing that each vial meets consistent, reproducible quality benchmarks.

Quality Control & Lyophilisation Integrity

The lyophilisation process employed in the manufacture of this peptide removes residual moisture under controlled vacuum conditions, preserving primary and tertiary structure across the product’s shelf life. Sterile glass vials are sealed under inert atmosphere to prevent oxidative degradation and microbial contamination. Each vial is inspected for physical integrity, and batch records are maintained to support audit requirements in regulated research environments. This rigorous quality control framework ensures that researchers receive a product that performs reliably across repeated experimental cycles.

Safety, Handling & Laboratory Precautions

IGF-1 LR3 Peptide Vial is intended solely for use by trained, qualified research professionals operating within appropriately equipped laboratory facilities. Standard laboratory precautions apply:

• Wear appropriate personal protective equipment (PPE), including gloves, lab coat, and eye protection.
• Handle in a clean, controlled environment to minimise contamination risk.
• Avoid repeated freeze-thaw cycles, which may compromise peptide integrity.
• Dispose of all materials in accordance with institutional biosafety and waste-management protocols.
• This compound is not evaluated for safety in humans or animals and must not be administered to any living organism.

Reconstitution, Packaging & Storage

IGF-1 LR3 is supplied as a lyophilised powder in a sterile, sealed glass vial. Reconstitution should be performed using laboratory-grade solvents appropriate to the intended experimental protocol and in strict accordance with institutional standard operating procedures. Once reconstituted, aliquot immediately to avoid degradation and store at −20 °C. Avoid exposure to direct light and repeated temperature fluctuations. Packaging is designed to maintain product integrity during transit and long-term laboratory storage.

Intended Research Use & Market Positioning

IGF-1 LR3 is an established research reagent used in the scientific investigation of growth factor receptor signalling, anabolic cellular pathways, tumour biology models, and tissue-culture studies. It is widely referenced in peer-reviewed literature examining IGF-1 receptor activation, downstream PI3K/Akt/mTOR signalling cascades, and comparative studies between native IGF-1 and modified analogues. Direct Anti Peptide positions this product as a premium, competitively priced research peptide for sale to academic institutions, contract research organisations, and licensed biotechnology laboratories globally.

Ordering, Availability & Fulfilment

Buy IGF-1 LR3 Peptide Vial online through Direct Anti Peptide’s secure eCommerce platform. We offer competitive best-price positioning, fast order processing, and discreet, compliant packaging for domestic and international shipments. Orders are fulfilled promptly from quality-controlled stock, and our customer support team is available to assist with CoA requests, bulk pricing enquiries, and shipment tracking. Order now to secure your research supply at the best available price.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. IGF-1 LR3 Peptide Vial is sold exclusively as a laboratory research reagent. It has not been approved by any regulatory authority for therapeutic, prophylactic, or diagnostic use in humans or animals. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international laws and regulations governing the procurement, handling, and use of research peptides. Direct Anti Peptide assumes no liability for misuse or use outside the stated research context.