Semax Nasal Spray

Semax Nasal Spray is a high-purity synthetic peptide compound available exclusively for laboratory and scientific research applications. Supplied at ≥98% purity and rigorously verified by HPLC and mass spectrometry, this formulation is offered by Direct Anti Peptide for qualified researchers seeking a reliable, analytically confirmed source. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

Semax is a synthetic heptapeptide analog of the adrenocorticotropic hormone (ACTH) fragment 4–10, developed and extensively studied for its nootropic and neuroprotective properties in preclinical research settings. It has attracted significant scientific interest due to its capacity to modulate brain-derived neurotrophic factor (BDNF) expression, support neural repair mechanisms, and influence serotonergic activity. Research literature documents its investigation across cognitive performance, neuroprotection, and neurological recovery models, making it a compelling subject for neuroscience and pharmacology research programs.

Peptide Structure & Amino Acid Sequence

Semax is structurally derived from the ACTH(4–10) peptide fragment and is represented by the amino acid sequence Met-Glu-His-Phe-Pro-Gly-Pro. This heptapeptide sequence confers resistance to rapid enzymatic degradation compared to its parent compound, extending its functional half-life in experimental models. Its structural configuration enables interaction with neurotrophin signaling pathways, particularly those associated with BDNF upregulation, making it a valuable tool in neurotrophic and cognitive research paradigms.

Chemical & Physical Characteristics

• Peptide Type: Synthetic heptapeptide, ACTH(4–10) analog
• Molecular Formula: C₃₇H₅₁N₉O₁₀S
• Molecular Weight: Approximately 813.93 g/mol
• Appearance: Clear to slightly opalescent aqueous nasal spray solution
• Solubility: Water-soluble; formulated in sterile aqueous solution
• CAS Number: 80714-61-0

Purity & Analytical Verification (HPLC & MS)

Every batch of Semax Nasal Spray supplied by Direct Anti Peptide is manufactured to a minimum purity of ≥98%, confirmed through high-performance liquid chromatography (HPLC). Mass spectrometry (MS) analysis is additionally performed to verify molecular identity and confirm the absence of truncated sequences, deletion peptides, or unintended synthesis by-products. Researchers can be confident that the compound received reflects the stated sequence and concentration, supporting reproducible experimental outcomes.

Quality Control & Lyophilization Integrity

While the nasal spray format is delivered as a pre-formulated aqueous solution rather than a lyophilized powder, Direct Anti Peptide applies stringent quality control protocols throughout production and packaging. Batch-level documentation is maintained to ensure consistency across production runs. Each unit undergoes integrity checks to confirm fill volume accuracy, container closure integrity, and solution clarity prior to dispatch. These measures are designed to preserve peptide stability and support the reliability of downstream research data.

Safety, Handling & Laboratory Precautions

Semax Nasal Spray is supplied strictly for in vitro and laboratory research use by trained scientific professionals. This compound must be handled in accordance with applicable institutional biosafety guidelines and standard laboratory precautions. Researchers should wear appropriate personal protective equipment (PPE), including gloves and eye protection, when handling peptide solutions. This product is not approved for administration to humans or animals, and any such use is strictly prohibited. Store away from unauthorized personnel and dispose of in accordance with local regulatory requirements.

Reconstitution, Packaging & Storage

Semax Nasal Spray is supplied as a ready-to-use aqueous solution in a metered nasal spray bottle. No reconstitution is required. Upon receipt, the product should be stored at 2–8°C (refrigerated) and protected from direct light and excessive heat. Avoid repeated freeze-thaw cycles, which may compromise solution integrity. When stored under recommended conditions, the product maintains its stated purity and concentration for the duration of the labeled shelf life. Always inspect the solution for visible particulates or discoloration before use in experimental protocols.

Intended Research Use & Market Positioning

Semax is actively investigated in neuroscience research for its role in modulating BDNF expression, supporting neuronal survival, and influencing serotonergic and dopaminergic signaling pathways. Preclinical studies have explored its potential applications in models of ischemic stroke recovery, cognitive decline, attention-related disorders, and mental fatigue. It is also studied as a neuroprotective agent in oxidative stress and neuroinflammation models. Direct Anti Peptide positions this compound as a premium-grade research tool for academic institutions, pharmaceutical research organizations, and independent laboratories engaged in CNS and neurological research.

Ordering, Availability & Fulfillment

Researchers can buy Semax Nasal Spray online directly through Direct Anti Peptide with confidence in product quality, batch traceability, and prompt fulfillment. We offer competitive pricing and maintain consistent stock availability to support ongoing research programs. Orders are processed efficiently and dispatched with appropriate cold-chain packaging to preserve solution integrity during transit. For bulk orders or institutional procurement inquiries, our team is available to discuss volume pricing and fulfillment logistics.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Semax Nasal Spray is sold exclusively as a laboratory research reagent. Direct Anti Peptide makes no claims regarding therapeutic efficacy, safety for human consumption, or suitability for any medical or veterinary application. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international laws and regulations governing the procurement, possession, and use of research peptides. This product must only be used by qualified research professionals in appropriately licensed laboratory environments.