PTD-DBM GHK-Cu Peptide Stack

Product Overview

The PTD-DBM GHK-Cu Peptide Stack, available exclusively through Direct Anti Peptide, combines two of the most extensively studied peptides in dermatological and hair follicle research into a single, convenient research bundle. PTD-DBM (Protein Transduction Domain-Domain Binding Motif) and GHK-Cu (Copper Tripeptide-1) have each demonstrated significant activity in preclinical models, and their combined use offers researchers a powerful dual-mechanism tool for investigating skin biology, follicular cycling, collagen synthesis, and tissue remodeling at the molecular level. This stack is offered for sale at a competitive price, with fast order fulfillment and strict quality assurance at every stage.

Peptide Structure & Amino Acid Sequence

PTD-DBM is a synthetic peptide engineered to penetrate cellular membranes and interfere with the protein–protein interaction between CXXC5 and Dishevelled (Dvl), an upstream regulator within the Wnt/β-catenin signaling cascade. By disrupting this interaction, PTD-DBM restores downstream Wnt/β-catenin activity, a pathway critically involved in hair follicle development, anagen induction, and follicular progenitor cell proliferation. Preclinical studies conducted in murine models — including both PTD-DBM-treated and CXXC5 knock-out subjects — have demonstrated measurable improvements in hair regrowth metrics linked to restored Wnt/β-catenin signaling.

GHK-Cu (Glycyl-L-Histidyl-L-Lysine : Copper) is a naturally occurring tripeptide-copper complex with a well-characterized role in wound healing, collagen and glycosaminoglycan synthesis, antioxidant defense, and extracellular matrix remodeling. GHK-Cu has been studied extensively for its capacity to modulate gene expression, upregulate tissue repair pathways, and promote dermal fibroblast activity. Together, these two peptides present complementary mechanisms that make this stack an ideal research tool for multi-pathway skin and follicle biology investigations.

Chemical & Physical Characteristics

• PTD-DBM: Synthetic cell-penetrating peptide; molecular target — CXXC5/Dvl interaction; Wnt/β-catenin pathway modulator
• GHK-Cu: Tripeptide-copper complex; molecular formula Cu·C₁₄H₂₄N₆O₄; CAS No. 89030-95-5
• Physical form: White to off-white lyophilized powder
• Solubility: Soluble in aqueous buffer systems under standard laboratory conditions
• Storage stability: Stable under recommended cold storage conditions when kept lyophilized and desiccated

Purity & Analytical Verification (HPLC & MS)

Every batch of the PTD-DBM GHK-Cu Peptide Stack supplied by Direct Anti Peptide is manufactured to a minimum purity specification of ≥98%, as confirmed by high-performance liquid chromatography (HPLC). Mass spectrometry (MS) is additionally employed to verify the correct molecular weight and structural identity of each peptide component. Certificates of Analysis (CoA) are available upon request and reflect batch-specific analytical data, ensuring full traceability and scientific reproducibility for research teams requiring documented quality benchmarks.

Quality Control & Lyophilization Integrity

Both PTD-DBM and GHK-Cu within this stack are produced under stringent quality control protocols. Lyophilization is performed under controlled conditions to preserve peptide conformation, biological activity, and long-term stability. Each vial is sealed under inert atmosphere to minimize oxidative degradation. Lyophilized peptides are inherently more stable than liquid formulations, providing researchers with extended shelf life and reliable batch-to-batch consistency — critical factors for longitudinal or comparative research programs.

Safety, Handling & Laboratory Precautions

This product is intended exclusively for use by trained laboratory professionals in controlled research environments. Standard laboratory personal protective equipment (PPE) — including gloves, eye protection, and appropriate lab coats — should be worn when handling this material. Researchers should consult applicable institutional biosafety guidelines and Safety Data Sheets (SDS) prior to use. This peptide stack must not be administered to humans or animals under any circumstances. Avoid inhalation of lyophilized powder and prevent contact with mucous membranes.

Reconstitution, Packaging & Storage

The PTD-DBM GHK-Cu Peptide Stack is supplied as individual lyophilized vials packaged together for researcher convenience. Reconstitution should be performed using appropriate research-grade solvents as determined by the investigator’s experimental protocol and institutional guidelines. Once reconstituted, solutions should be aliquoted and stored according to standard peptide handling procedures to minimize freeze-thaw degradation. Lyophilized vials should be stored at −20°C or below, protected from light and moisture, until the point of use. Shipping is conducted with appropriate cold-chain packaging to maintain product integrity during transit.

Intended Research Use & Market Positioning

The PTD-DBM GHK-Cu Peptide Stack is positioned as a premium dual-peptide research tool for scientists investigating hair follicle biology, dermal regeneration, Wnt/β-catenin pathway modulation, and copper-dependent tissue repair mechanisms. It is particularly suited for in vitro cell culture studies, ex vivo tissue models, and preclinical animal research. Direct Anti Peptide offers this stack for sale to qualified research institutions, academic laboratories, and independent investigators seeking high-purity, analytically verified peptides at the best price available online.

Ordering, Availability & Fulfillment

Buy the PTD-DBM GHK-Cu Peptide Stack online today through Direct Anti Peptide’s secure eCommerce platform. Orders are processed promptly, with cold-chain compliant packaging and expedited fulfillment options available. Our team is committed to providing researchers with reliable access to high-purity research peptides at competitive prices. Order now to take advantage of our current pricing and ensure uninterrupted supply for your ongoing research programs.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. The PTD-DBM GHK-Cu Peptide Stack is sold strictly as a laboratory research reagent. Direct Anti Peptide makes no claims regarding therapeutic efficacy, safety for administration, or suitability for any use outside of controlled scientific research. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international regulations governing the acquisition, handling, and use of research peptides. This product must not be used as a drug, supplement, cosmetic ingredient, or in any application involving living subjects outside of formally approved research protocols.