Protirelin TRH Peptide Vial

Protirelin TRH Peptide Vial is a premium-grade, ≥98% purity lyophilised research peptide available for sale at Direct Anti Peptide. Designed exclusively for qualified laboratory professionals, this compound supports advanced investigations into neuroendocrine signalling, thyroid hormone regulation, and related hormonal pathway research. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

Protirelin, commonly referred to as Thyrotropin-Releasing Hormone (TRH), is a tripeptide hormone naturally synthesised in the hypothalamus. As a research tool, it has become indispensable for scientists exploring the hypothalamic-pituitary-thyroid (HPT) axis, neuroendocrine feedback loops, and complex hormonal secretion mechanisms. Direct Anti Peptide supplies this compound in a sterile glass vial as a lyophilised powder, ensuring maximum stability and ease of handling within controlled laboratory environments. Researchers worldwide rely on this versatile peptide to generate reproducible, high-quality experimental data.

Peptide Structure & Amino Acid Sequence

Protirelin TRH is a tripeptide with the sequence pGlu-His-Pro-NH₂ (pyroglutamyl-histidyl-proline amide). This compact but highly bioactive structure is characterised by an N-terminal pyroglutamate residue and a C-terminal proline amide, both of which contribute to its notable resistance to enzymatic degradation compared to linear peptides. The molecular formula is C₁₆H₂₂N₆O₄, with a molecular weight of approximately 362.39 g/mol. Its CAS number is 24305-27-9. This well-defined tripeptide architecture makes it a reliable and consistent reference compound for neuroendocrine research protocols.

Chemical & Physical Characteristics

• Chemical Name: Thyrotropin-Releasing Hormone (TRH) / Protirelin
• CAS Number: 24305-27-9
• Molecular Formula: C₁₆H₂₂N₆O₄
• Molecular Weight: ~362.39 g/mol
• Sequence: pGlu-His-Pro-NH₂
• Appearance: White to off-white lyophilised powder
• Solubility: Soluble in aqueous laboratory solvents under standard research conditions
• Purity: ≥98% (HPLC verified)

Purity & Analytical Verification (HPLC & MS)

Every batch of Protirelin TRH Peptide Vial supplied by Direct Anti Peptide undergoes rigorous analytical verification to confirm a minimum purity of ≥98%. High-Performance Liquid Chromatography (HPLC) is employed to quantify purity and detect any trace impurities, while Mass Spectrometry (MS) confirms the correct molecular identity and structural integrity of the compound. These dual analytical methods provide researchers with a high level of confidence in the compound’s consistency and reliability across experimental replicates. Certificates of Analysis (CoA) are available upon request, providing full transparency for laboratory documentation and compliance purposes.

Quality Control & Lyophilisation Integrity

Protirelin TRH is supplied in a lyophilised (freeze-dried) format, which is the industry-standard method for preserving peptide stability during storage and transit. The lyophilisation process removes residual moisture under vacuum conditions, significantly extending shelf life and preventing degradation of the peptide’s primary structure. Each vial is sealed under inert conditions to protect against oxidation and environmental contamination. Direct Anti Peptide’s quality control procedures encompass every stage of production and packaging, ensuring that researchers receive a product that meets the highest standards of scientific integrity.

Safety, Handling & Laboratory Precautions

This compound is intended exclusively for use by trained research professionals operating within appropriately equipped laboratory facilities. Standard laboratory personal protective equipment (PPE), including gloves, lab coat, and eye protection, should be worn at all times when handling this peptide. Researchers must adhere to their institution’s chemical safety guidelines and applicable regulatory frameworks. This product is not approved for human or animal administration and must never be used outside of a controlled research setting. Disposal should comply with local and institutional waste management regulations.

Reconstitution, Packaging & Storage

The Protirelin TRH Peptide Vial is supplied as a lyophilised powder in a sealed, sterile glass vial. For laboratory reconstitution, researchers should use an appropriate aqueous solvent as determined by their specific experimental protocol. Upon reconstitution, aliquoting and prompt use or proper storage is recommended to preserve compound integrity. The lyophilised powder should be stored at -20°C in a dry, dark environment, away from repeated freeze-thaw cycles. Reconstituted solutions should be stored at 4°C and used within a timeframe consistent with established laboratory best practices.

Intended Research Use & Market Positioning

Protirelin TRH is widely utilised in neuroendocrine research, particularly in studies examining the hypothalamic-pituitary-thyroid axis, hormonal feedback regulation, and pituitary responsiveness. It is also investigated in the context of neuroprotection research and central nervous system signalling studies. Direct Anti Peptide positions this compound as a premium, competitively priced research tool for academic institutions, pharmaceutical research organisations, and independent laboratories seeking a reliable, high-purity TRH reference peptide. It is not intended for therapeutic, diagnostic, or any consumptive application.

Ordering, Availability & Fulfillment

Direct Anti Peptide offers Protirelin TRH Peptide Vial for sale online with straightforward ordering, competitive best pricing, and reliable fulfillment. Researchers can order now through our secure eCommerce platform, with prompt dispatch and discreet, protective packaging to maintain vial integrity during transit. Bulk enquiries and institutional purchasing are welcomed — contact our team for volume pricing and availability information. We are committed to providing a seamless buying experience for research professionals worldwide.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Protirelin TRH Peptide Vial is sold exclusively as a laboratory research compound. It has not been evaluated or approved by any regulatory authority for therapeutic or diagnostic use in humans or animals. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international laws and regulations governing the purchase, storage, handling, and use of research peptides. Direct Anti Peptide accepts no liability for misuse or use outside of intended research applications.