Tesamorelin Sermorelin

Direct Anti Peptide offers the Tesamorelin Sermorelin peptide stack at ≥98% purity, rigorously verified by HPLC and mass spectrometry analysis. This dual-peptide research combination is supplied in lyophilized form and is intended exclusively for qualified laboratory and scientific research applications. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

The Tesamorelin Sermorelin stack represents a compelling dual-peptide research formulation that combines two well-characterized growth hormone-related peptides. Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH), engineered to stimulate endogenous growth hormone secretion from the anterior pituitary gland. Sermorelin, a 29-amino acid peptide fragment of GHRH, similarly acts on pituitary receptors to promote growth hormone production. Together, these two peptides have attracted significant academic and preclinical research interest due to their complementary mechanisms and their potential to produce synergistic effects on growth hormone axis modulation. This stack is available for sale at Direct Anti Peptide and is positioned as a premium research-grade product for institutional and independent laboratory use.

Peptide Structure & Amino Acid Sequence

Tesamorelin is a synthetic peptide consisting of the full 44-amino acid sequence of human GHRH, conjugated with a trans-3-hexenoic acid group at its N-terminus to enhance stability and bioavailability in research settings. Its molecular formula is C₂₂₁H₃₆₆N₇₂O₆₇S with a molecular weight of approximately 5135.8 Da. Sermorelin comprises the first 29 amino acids of endogenous GHRH (GHRH 1-29 NH₂) and retains full biological activity at the GHRH receptor. Its molecular formula is C₁₄₉H₂₄₆N₄₄O₄₂S with a molecular weight of approximately 3357.9 Da. Both peptides are synthesized using solid-phase peptide synthesis (SPPS) protocols to ensure sequence fidelity and structural integrity.

Chemical & Physical Characteristics

• Tesamorelin: White to off-white lyophilized powder; soluble in aqueous buffer; CAS No. 218949-48-5
• Sermorelin: White to off-white lyophilized powder; soluble in sterile aqueous solution; CAS No. 86168-78-7
• Appearance: Lyophilized solid, free of visible particulates
• Purity: ≥98% for both peptide components, confirmed by HPLC
• Storage Temperature: −20°C (long-term); 2–8°C (short-term use)

Purity & Analytical Verification (HPLC & MS)

Every batch of the Tesamorelin Sermorelin stack supplied by Direct Anti Peptide undergoes stringent analytical testing prior to dispatch. High-performance liquid chromatography (HPLC) is employed to confirm peptide purity at ≥98%, while mass spectrometry (MS) is used to verify the correct molecular weight and structural identity of each component. These dual-verification protocols ensure that researchers receive consistent, publication-ready material that meets the highest standards of analytical quality available in the research peptide market.

Quality Control & Lyophilization Integrity

Both Tesamorelin and Sermorelin are lyophilized under controlled conditions to preserve structural stability and maximize shelf life. The lyophilization process removes residual moisture without degrading the peptide backbone, ensuring that each vial contains intact, biologically representative material. Batch-specific certificates of analysis (CoA) are available upon request and document HPLC purity, MS confirmation, and physical appearance for full traceability and research documentation compliance.

Safety, Handling & Laboratory Precautions

This product is intended exclusively for use by trained research professionals in properly equipped laboratory environments. Appropriate personal protective equipment (PPE), including gloves, lab coat, and eye protection, should be worn at all times when handling lyophilized peptide materials. Researchers should follow all applicable institutional biosafety guidelines and local regulatory requirements when working with research-grade peptides. This product is not approved for any use outside of controlled research settings.

Reconstitution, Packaging & Storage

Each vial in the Tesamorelin Sermorelin stack should be reconstituted using a suitable aqueous solvent appropriate for the specific research protocol being conducted. Reconstituted solutions should be handled, aliquoted, and stored strictly in accordance with institutional laboratory protocols. For long-term preservation, store lyophilized vials at −20°C in a dry, dark environment. Avoid repeated freeze-thaw cycles, which may compromise peptide integrity. Packaging is designed to maintain product stability throughout transit and storage.

Intended Research Use & Market Positioning

The Tesamorelin Sermorelin peptide stack is designed for preclinical and in vitro research investigations focused on growth hormone axis biology, pituitary receptor pharmacology, body composition modulation mechanisms, and related metabolic pathways. Published literature has explored Tesamorelin’s role in models of lipodystrophy and visceral fat accumulation, while Sermorelin has been studied in the context of somatotropic axis stimulation and age-related decline in growth hormone secretion. This stack offers researchers a convenient, cost-effective format to explore the combined or comparative effects of two structurally distinct GHRH-related peptides within a single research program.

Ordering, Availability & Fulfillment

The Tesamorelin Sermorelin stack is available to buy online now through Direct Anti Peptide. We offer competitive best-price fulfillment with fast dispatch, secure packaging, and full order tracking. All orders are processed promptly and shipped with appropriate cold-chain considerations to preserve product integrity during transit. Researchers and institutions are encouraged to order now to take advantage of our consistent stock availability and transparent CoA documentation policy.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. The Tesamorelin Sermorelin peptide stack is sold exclusively as a laboratory research reagent. Direct Anti Peptide makes no claims regarding the therapeutic, pharmacological, or physiological effects of this product in humans or animals. All purchasers are solely responsible for ensuring compliance with applicable local, national, and international regulations governing the procurement, handling, and use of research peptides. This product has not been evaluated or approved by any regulatory authority for use outside of research contexts.